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ZEG Berlin GmbH

Zentrum für Epidemiologie und Gesundheitsforschung

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Nils Kossack

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Publications

Schultze Michael, Kossack Nils, Kromer Christian, Zimmermann Thomas M., Kolb Nikolaus, Epidemiology of generalized pustular psoriasis in Germany: Analyzing factors influencing prevalence estimates from claims data. JDDG: J Dtsch Dermatol Ges.. 2025; 10.1111/ddg.15633.
Pinter Andreas, Schulte Marcus, Kossack Nils, Pignot Marc, Schultze Michael, Feldhus Andrea, Real-world psoriasis treatment patterns and disease burden in Germany, with a focus on biologics and apremilast: data from a German statutory health insurance database JME: Journal of Medical Economics. 2025; VOL. 28, NO. 1, 207-220. 10.1080/13696998.2025.2452054.
Hering Kathrin, Kuhnt Thomas, Kossack Nils, Richter Lena M., Schultze Michael, Osowski Ulrike, Henkel Luisa, Gaupel Ann-Christin, Solbes Marie-Noelle, Zolyniak Bernard, Schoenherr Nancy, Real-world treatment patterns and survival outcomes in patients with locally advanced squamous cell carcinoma of the head and neck in Germany using claims data Front. Oncol. 2025; Vol. 15:1547311. 10.3389/fonc.2025.1547311.
Atmaca Akin, Grohé Christian, Klinghardt Moritz, Kossack Nils, Pignot Marc, Schuh Roxana, A Real-World Evaluation of Brain Imaging in Patients with Advanced Non-Small Cell Lung Cancer: Insights from a German Claims Data Analysis Oncol Res Treat. 2025; 10.1159/000547215.
Tarcyane Barata Garcia, Kossack Nils, Pignot Marc, Dagher Mohammed, Schuster Alexander K., Wielink Kun Shi-van, Epidemiology and burden of mild/moderate versus high myopia in Germany: A claims data analysis. Acta Ophthalmologica. 2025; 10.1111/aos.17589.
Ständer Sonja, Ketz Miriam, Akumo Divine, Kossack Nils, Pignot Marc, Chavda Rajeev, Gabriel Sylvie, Comorbidities, healthcare resource utilization & treatment pattern among patients with prurigo nodularis, compared to a benchmark in Germany: A real-world evidence claims data study J Eur Acad Dermatol Venerol. 2023; 1-12. 10.1111/jdv.19700.
O'Kelly James, Bartsch Robert, Kossack Nils, Borchert Julia, Pignot Marc, Hadji Peyman, Real-world effectiveness of osteoporosis treatments in Germany. Arch Osteoporos. 2022; 10.1007/s11657-022-01156-z.
Ständer Sonja, Ketz Miriam, Kossack Nils, Akumo Divine, Pignot Marc, Chavda Rajeev, Gabriel Sylvie, Clinical and Economic Burden Among Patients With Prurigo Nodularis Compared To A Benchmark In Germany: A Real-World-Evidence Claims Data Study. ISPOR Europe 2022, 6 - 9 November. 2022;
Ständer Sonja, Ketz Miriam, Kossack Nils, Pignot Marc, Chavda Rajeev, Gabriel Sylvie, Disease Burden, Healthcare Resource Utilization & Treatment Pattern among Patients with Prurigo Nodularis compared to a Benchmark in Germany: A Real-World-Evidence Claims Data Study. 31st EADV Congress, Milan. 2022;
Vogelmeier Claus F., Diesing Joanna, Kossack Nils, Pignot Marc, Friedrich Felix W., COPD Exacerbation History and Impact on Future Exacerbations – 8-Year Retrospective Observational Database Cohort Study from Germany. International Journal of Chronic Obstructive Pulmonary Disease. 2021; 2407–2417.
Birkeland Kåre I., Bodegard Johan, Banerjee Amitava, Kim Dae Jung, Norhammar Anna, Eriksson Jan W., Thuresson Marcus, Okami Suguru, Ha Kyoung Hwa, Kossack Nils, Mamza Jil Billy, Zhang Ruiqi, Yajima Toshitaka, Komuro Issei, Kadowaki Takashi, Lower cardiorenal risk with sodium glucose cotransporter-2 inhibitors versus dipeptidyl peptidase-4 inhibitors in patients with type 2 diabetes without cardiovascular and renal diseases: A large multinational observational study. Diabetes Obes Metab.. 2021; 23:75–85. 10.1111/dom.14189.
Ständer Sonja, Ketz Miriam, Kossack Nils, Akumo Divine, Pignot Marc, Gabriel Sylvie, Chavda Rajeev, Epidemiology of Prurigo Nodularis compared with Psoriasis in Germany: A Claims Database Analysis. Acta Dermato-Venereologica. 2020; 100 (18): adv00309. 10.2340/00015555-3655.
Kossack Nils, Schoenfelder T., Schultze Michael, Pignot Marc, Mehta S., Nazareth T., Walzer S., Real-World Cost Difference in Patients With Psoriasis Initiating Apremilast vs. Secukinumab After Conventional Systemic Therapy Using German Sickness Fund Data DDK KOMPAKT 2020. JDDG Volume 18 Issue S1. 2020. 2020; 10.1111/ddg.14021.
O'Kelly James, Bartsch Robert, Kossack Nils, Borchert Julia, Pignot Marc, Hadji Peyman, Real-World Effectiveness of Osteoporosis Treatments in Germany Value in Health, Volume 23. 2020; S592. 10.1016/j.jval.2020.08.1134.
Kossack Nils, Schoenfelder T., Schultze Michael, Pignot Marc, Mehta S., Nazareth T., Walzer S., Real-World Cost Difference in Patients with Psoriasis Newly Initiating Apremilast vs. Biologic Treatment after Conventional Systemic Therapy: A Retrospective Analysis of German Sickness Fund Data. Value in Health (22). 2019; 10.1016/j.jval.2019.09.2645.

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Executive Team

  • Clare Barnett
  • Karl Pauls
  • Michael Schultze
  • Alfred Pauls
  • Do Minh Thai
  • Elisabeth Finger
  • Jens A. Lange
  • Antje Simon

Management Board

  • Klaas Heinemann
  • Clare Barnett
  • Marc Pignot
  • Karl Pauls
  • Johanna Poppe

Project Management Team

  • Pauline De Corte
  • Lisa Eggebrecht
  • Mohammed Dagher
  • Armin Papkalla
  • Silke Zimmermann
  • Nik Kolb

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ZEG Berlin

Berlin Center for Epidemiology and Health Research

Invalidenstraße 115
10115 Berlin
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Expertise

  • Real-World Evidence
  • Non-interventional study design
  • Post-authorization safety studies
  • Post-authorization efficacy studies
  • Cohort studies
  • Case-control studies
  • Medical Devices
  • Patient Reported Outcomes (PROs)
  • Data collection instruments

Services

  • Crisis Management
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  • Data Management and Biostatistics
  • Medical Writing
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  • Pharmacovigilance

ENCePP

We are a partner centre of the ENCePP scientific network which is coordinated by the European Medicines Agency. We are dedicated to excellence in research by adhering to the ENCePP Guide on Methodological Standards and promoting scientific independence and transparency. We register studies in the ENCePP E-Register of Studies, a publicly accessible resource for the registration of pharmacoepidemiological and pharmacovigilance studies.

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With a view to the introduction of the GDPR/EUDSGVO we are glad to present our newupdated privacy policy . The updated description are stored under “about us” and then “privacy policy/GDPR”. Further translation for study participants will follow contemporary.

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