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ZEG Berlin GmbH

Zentrum für Epidemiologie und Gesundheitsforschung

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About MRS

Women develop typical complaints while aging

Age-related declines in physical and mental capacity are common. Many women experience symptoms such as periodic sweating or hot flushes, depression, insomnia, impaired memory, lack of concentration, nervousness, and bone & joint complaints.

Spontaneous and unexpected sweating, particularly at night, is a key symptom for women in their menopausal transition.  Men also commonly complain about sweats and we believe that episodes of sweating may be an important symptom of changes in the course of aging.

The Menopause Rating Scale (MRS) was developed in response to the lack of standardized scales to measure the severity of aging-symptoms and their impact on the health-related Quality of Life (HRQoL) in the 1990s . A scale was designed to be easily completed by women, not by their physicians 1. 

Key objectives

  • To measure health-related quality of life (QoL) or severity of complaints in aging women
  • To measure changes over time and across different cultures (MRS scale available in 25 languages)
  • To measure changes before/ after treatment of with hormone replacement therapy
  • To measure in a standardized way

Further information on the use of the MRS and available languages can be found here.

 


1. Hauser GA, Huber IC, Keller PJ, Lauritzen C, Schneider HPG: Evaluation der klinischen Beschwerden (Menopause Rating Scale). Zentralbl Gynakol 1994; 116:16-23.

 

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ZEG Berlin

Berlin Center for Epidemiology and Health Research

Invalidenstraße 115
10115 Berlin
Germany

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Expertise

  • Real-World Evidence
  • Non-interventional study design
  • Post-authorization safety studies
  • Post-authorization efficacy studies
  • Cohort studies
  • Case-control studies
  • Medical Devices
  • Patient Reported Outcomes (PROs)
  • Data collection instruments

Services

  • Crisis Management
  • Consulting
  • Data Management and Biostatistics
  • Medical Writing
  • Study Management
  • Quality Assurance
  • Pharmacovigilance

ENCePP

We are a partner centre of the ENCePP scientific network which is coordinated by the European Medicines Agency. We are dedicated to excellence in research by adhering to the ENCePP Guide on Methodological Standards and promoting scientific independence and transparency. We register studies in the ENCePP E-Register of Studies, a publicly accessible resource for the registration of pharmacoepidemiological and pharmacovigilance studies.

General Data Protection Regulation

With a view to the introduction of the GDPR/EUDSGVO we are glad to present our newupdated privacy policy . The updated description are stored under “about us” and then “privacy policy/GDPR”. Further translation for study participants will follow contemporary.

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