• Skip to primary navigation
  • Skip to main content
  • Skip to primary sidebar
  • Skip to footer

ZEG Berlin GmbH

Zentrum für Epidemiologie und Gesundheitsforschung

  • Home
  • Expertise
    • Real-World Evidence
    • Non-interventional study design
    • Post-authorization safety studies
    • Post-authorization efficacy studies
    • Cohort studies
    • Case-control studies
    • Medical Devices
    • Diagnostic tools
      • Research team
    • Data collection instruments
  • Services
    • RWE Services
    • Crisis Management
    • Consulting
    • Data Management and Biostatistics
    • Medical Writing
    • Study Management
    • Quality Assurance
    • Pharmacovigilance
  • Library & News
    • News/Conferences
    • Publications
  • About Us
    • Who We Are
      • Management Board
      • Executive Team
      • Project Management Team
    • History
    • Careers
    • Data Protection Information
  • Contact

Cohort studies

Studies link cohorts by a medical device, diagnostic tool or medication

ZEG Berlin conducts non-interventional cohort studies where study participants (the cohort) are linked by a medication, medical device or diagnostic tool.

Prospective

Subjective patient experiences understood through careful study design

EURAS/INAS is a prospective, primary-data, patient-reported outcome, cohort study design that is adaptable to your needs. Using raw data collected from physicians and patients, we gather targeted and potentially sensitive information that is not easily accessed through normal big data pathways (e.g. claims / electronic medical record databases). Potential confounding variables such as sexual behavior, breastfeeding, pain, and mood are not consistently collected by these sources.

We are currently conducting large prospective studies requiring the collection of sensitive and/or subjective data from the patients. The collection of this information would not be possible without the use of primary data collection and a carefully developed study design.

Retrospective

Finding the way through a constellation of disease medication and events

Occasionally a constellation of disease, medication, and events makes conducting large-scale cohort studies or case-control studies unfeasible with targeted information on adverse events not easily found in registry data. Such was the case when ZEG Berlin conducted a small, retrospective, cross-sectional study on the treatment in pediatric patients living with hepatitis C. Using data collected from specialized pediatric hepatic clinics, we successfully described demographic and disease characteristics of patients within this population and estimated exposure to medications.

Single-arm study

Comparison groups are not always needed to see clear patterns.

In specific situations, it may be useful to monitor the frequency of certain safety events in a new device or medication without comparison to a group of non-users. This is the case when there is no relevant comparator group, or the absolute frequency of a rare or very-rare risk is of primary concern.

ZEG Berlin has managed several single-arm studies in the US and Europe including prospective and retrospective drug utilization studies assessing prescription patterns and prospective medical device safety studies.

sidebar

Expertise

  • Real-World Evidence
  • Non-interventional study design
  • Post-authorization safety studies
  • Post-authorization efficacy studies
  • Cohort studies
  • Case-control studies
  • Medical Devices
  • Diagnostic tools
  • Data collection instruments

sidebar-alt

Footer

ZEG Berlin

Berlin Center for Epidemiology and Health Research

Invalidenstraße 115
10115 Berlin
Germany

Contact Us

Services

  • Crisis Management
  • Consulting
  • Data Management and Biostatistics
  • Medical Writing
  • Study Management
  • Quality Assurance
  • Pharmacovigilance

ENCePP

We are a partner centre of the ENCePP scientific network which is coordinated by the European Medicines Agency. We are dedicated to excellence in research by adhering to the ENCePP Guide on Methodological Standards and promoting scientific independence and transparency. We register studies in the ENCePP E-Register of Studies, a publicly accessible resource for the registration of pharmacoepidemiological and pharmacovigilance studies.

General Data Protection Regulation

With a view to the introduction of the GDPR/EUDSGVO we are glad to present our newupdated privacy policy . The updated description are stored under “about us” and then “privacy policy/GDPR”. Further translation for study participants will follow contemporary.

© 2011–2023 ZEG Berlin

Impressum

Website by Laura Yeffeth.