Where absolute risk is small, case-control studies may be the choice
Case-control studies may be preferred to large cohort studies when the absolute risk of an event is small. ZEG Berlin has undertaken a number of prospective and retrospective case-control studies often in response to a safety signal detected by either the Marketing Authorization Holder (MAH) or regulatory authorities through spontaneous adverse event reporting. Our network of health care professionals in rural and urban communities, as well as tertiary-level diagnostic centers, facilitates the quick and precise recruitment of your desired study population.
Some of our previous case-control studies include:
- Retrospective case-control study on the safety of phenacetin-free analgesics and end-stage renal failure
- Register-based case-control study on the risk of breast cancer and different hormone-replacement therapy formulations
- Several prospective and retrospective case-control studies on the risk of venous thromboembolism and the use of oral contraceptives.