ZEG Berlin GmbH

Zentrum für Epidemiologie und Gesundheitsforschung

Category: Publications

Unintended pregnancy rates differ according to combined oral contraceptive – results from the INAS-SCORE study.

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Yesterday, our latest publication, Unintended pregnancy rates differ according to combined oral contraceptive – results from the INAS-SCORE study was published online in the European Journal of Contraception and Reproductive Health Care.

The study was aimed at estimating the real-use contraceptive effectiveness of the combined oral contraceptive (COC) containing dienogest and oestradiol valerate (DNG/oEV) compared to other combined oral contraceptives (oCOC) and particularly, levonorgestrel-containing OCs (LNG).

The results confirmed that DNG/oEV showed improved contraceptive effectiveness compared with oCOC and particularly LNG-COC when adjusted for age, parity, user status, and smoking

Real world data on Nexplanon® procedure-related events: final results from the Nexplanon observational risk assessment study (NORA)

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Our latest publication, Real-world data on Nexplanon® procedure-related events: final results from the Nexplanon observational risk assessment study (NORA) has just been published in Contraception.

The study was aimed to characterize the frequency of insertion-, localization- and removal-related events and their clinically significant consequences among Nexplanon® (etonogestrel radiopaque contraceptive implant) users in the United States during standard clinical practice.

The finds confirmed that events associated with the insertion, localization, and removal of the Nexplanon contraceptive implant were rare and their clinical consequences were generally not suggestive of serious injury.

The study demonstrates that complications associated with insertion and removal of Nexplanon are rare when performed by trained clinicians.

Final results of from the EURAS-IUD extension study

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Our latest publication, Perforation risk and intra-uterine devices: results of the EURAS-IUD 5-year extension study, has just been published in the European Journal of Contraception and Reproductive Health Care.  This landmark observational study followed women for 5 years and identified intra-uterine device (IUD) perforations dectected from 12 to 60 months following IUD insertion.

The incidence of uterine perforations in this study was low, although higher than the commonly reported rate.  Clinical sequalae of perforations were generally mild and associated with a very low risk of injury.  You can download the full text of article using this link: Full Article